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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A2
All Species:
14.85
Human Site:
S494
Identified Species:
27.22
UniProt:
Q9UI40
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI40
NP_065077.1
661
73664
S494
L
P
D
V
R
K
P
S
S
R
K
F
F
P
I
Chimpanzee
Pan troglodytes
XP_528551
661
73638
S494
L
P
D
V
R
K
P
S
S
R
K
F
F
P
I
Rhesus Macaque
Macaca mulatta
XP_001108751
661
73840
S494
L
P
D
V
R
K
P
S
S
R
K
F
F
P
I
Dog
Lupus familis
XP_852036
664
74187
S497
L
P
D
V
R
K
P
S
S
R
K
F
F
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGQ8
605
66848
A448
I
T
A
T
L
W
I
A
V
F
S
Y
L
M
V
Rat
Rattus norvegicus
O54701
670
74638
A503
L
P
D
V
R
K
P
A
S
K
K
F
F
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514353
346
38802
G190
E
L
F
T
S
L
I
G
V
F
I
A
H
S
N
Chicken
Gallus gallus
Q9IAL7
651
72677
R484
L
P
D
V
R
N
P
R
S
R
K
F
F
P
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
V356
L
T
F
L
M
S
A
V
W
I
S
A
F
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6A0
888
95868
R724
L
P
D
T
R
T
P
R
G
K
R
F
F
P
V
Honey Bee
Apis mellifera
XP_396230
658
71609
R494
L
P
D
T
R
T
P
R
G
K
K
F
F
A
V
Nematode Worm
Caenorhab. elegans
NP_001040663
596
66359
S440
I
L
W
I
A
F
F
S
Y
L
M
V
W
W
A
Sea Urchin
Strong. purpuratus
XP_787540
651
70927
E484
L
P
D
V
R
R
V
E
S
R
K
W
Y
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.1
93.2
N.A.
35.2
88.6
N.A.
39.3
77
N.A.
31
N.A.
38.9
46.9
42.2
39.4
Protein Similarity:
100
99.8
98.6
95.3
N.A.
53.5
93.4
N.A.
44.9
86.8
N.A.
50.3
N.A.
53.2
61.2
60.3
53.8
P-Site Identity:
100
100
100
100
N.A.
0
86.6
N.A.
0
86.6
N.A.
13.3
N.A.
53.3
53.3
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
26.6
100
N.A.
0
86.6
N.A.
20
N.A.
73.3
66.6
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
16
0
0
0
16
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
16
0
0
8
8
0
0
16
0
62
70
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
16
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
16
0
0
8
0
0
16
0
0
8
8
0
0
0
47
% I
% Lys:
0
0
0
0
0
39
0
0
0
24
62
0
0
0
0
% K
% Leu:
77
16
0
8
8
8
0
0
0
8
0
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
70
0
0
0
0
62
0
0
0
0
0
0
54
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
70
8
0
24
0
47
8
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
39
54
0
16
0
0
16
0
% S
% Thr:
0
16
0
31
0
16
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
54
0
0
8
8
16
0
0
8
0
0
31
% V
% Trp:
0
0
8
0
0
8
0
0
8
0
0
8
8
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _